Brno Ph.D. Talent
Brno Ph.D. Talent
Sensitizing colorectal tumors to combined induction of p53 and ISR
Lector: Zdeněk Andrysík
Institution: Masaryk University, Faculty of Science
Field: Animal physiology, immunology and developmental biology
About the project
Despite advances in treatment, colorectal cancer remains one of the leading causes of cancer deaths. To improve patient outcomes, I am developing a specialized mouse model that allows us to track how cancer cells respond to drugs that target key cellular tumor-suppressive pathways. The aim of my project is to identify a drug combination that activates these pathways strongly enough to push cancer cells towards death. Ultimately, this approach could lead to more effective and precise therapies.
Why science?
Science gives me the chance to learn something new every day and to keep challenging myself. I also love that science is not limiting me to one place, but rather opens doors to travel, collaborate, and meet inspiring people from all over the world. But what truly motivates me is the idea that the work we do can leave a lasting mark. It’s amazing to think that the answers we uncover today could help improve lives not just now, but for generations to come.
What do I like most about Brno
What I like about Brno is that it offers all the opportunities of a big city, while still allowing easy access to nature - whether it's for a walk to clear your head or a quick horseback ride. As a student, I find everything I need here, and as a scientist, I benefit from being part of a vibrant research community. And above all, I was born here. My family and friends are here. Brno is my home.