Brno Ph.D. Talent

Mariane de Araujo e Silva

Non-invasive Vagus Nerve Temporal Interference Stimulation to Modulate and Predict Therapeutic Outcomes in Epilepsy

Lector: Dr Ing. Adam Williamson. Ph.D.

Institution: Masaryk University, Faculty of Medicine

Field: Neuroscience

 

About the project

Approximately one-third of epilepsy patients remain drug-resistant and have limited treatment options. This project investigates a novel, non-invasive approach—temporal interference stimulation of the vagus nerve—to influence epileptogenic brain networks. Using EEG connectivity and heart rate variability, we aim to identify biomarkers that predict individual responses, positioning TI-VNS as a promising therapy and a tool to guide future invasive interventions.

 

Why science?

I am driven by curiosity and a strong motivation to improve people’s lives through knowledge. Coming from a Latin, female, and low-income background, science became both a passion and a transformative opportunity. It enabled me to overcome social and economic barriers while pursuing excellence, and to contribute to research that can have a meaningful impact for individuals, communities, and society as a whole.

 

What do I like most about Brno

Brno offers an outstanding scientific environment, with state-of-the-art laboratories and high-quality research. The university infrastructure is excellent and supports academic development at all stages. Beyond science, Brno is a safe, welcoming city and an ideal place to build a family, offering a strong sense of stability and a positive perspective for the future.