Brno Ph.D. Talent

Vincent Jongen

Development of microfluidic systems for the modelling of lung tissue

Lector: Assoc. Prof. MVDr. Aleš Hampl, CSc.

Institution: Masaryk University, Faculty of Medicine

Field: Biomedical Sciences

 

About the project

Advances in stem cell research have led to the development of 3D in vitro models, or organoids. Organoids allow for the partial recapitulation of some aspects of lung tissue, however significant limitations remain. (e.g. lack of tissue architecture or concentration gradients of signaling molecules). This project aims to develop a microfluidic device that combines lung and endothelial progenitors to overcome these issues and drive morphogenesis of lung tissue in a controlled microenvironment.

 

Why science?

Working in science gives you the satisfying feeling that you contribute to the overall advancement to improve the life and health of many people. What's more, the work is always varied by combining desk work with experiments performed in the lab as well as participation in the occasional (international) conference.

 

What do I like most about Brno

Brno is a lively student-city with many univesities and research institutes to persue a career in science, while also providing many ways to spend your free time, with a large variety of theatres, museums, and pubs. Moreover, Brno is surrounded by beautiful nature and the city's location in the heart of Europe allows for amazing weekend trips.