Brno Ph.D. Talent

Miriam Sandanusova

Study of extracellular vesicles in the gastro-intestinal tract as a novel approach to inflammatory bowel disease treatment

Lector: Lukáš Kubala

Institution: Masaryk University, Faculty of Science

Field: Animal physiology, immunology and developmental biology


About the project

Inflammatory bowel disease (IBD) is a chronic disease, leading to serious health problems, often accompanied by dysbiosis and enrichment in certain bacterial species. In consequence, presumably also the production and composition of bacterial extracellular vesicles (EVs) in the gut change. In order to develop an effective cure for IBD, the role of microbiota-derived EVs should be considered; inhibition of pro-inflammatory EVs uptake by host cells may emerge as a promising approach for IBD cure.


Why science?

I am fascinated by nature and living organisms, particularly by the complexity of the human body.


What do I like most about Brno

I love the atmosphere of the city - friendly people, cozy coffee bars, lots of trees and peaceful pace of life.