Evolutionary and Genetic Engineering of Polyhydroxyalkanoates Producing Bacteria

Supervisor: doc. Ing. Stanislav Obruča, Ph.D.

Institution: Institute of Food Chemistry and Biotechnology, FCH BUT

Field of Study: Food Science

About my project

The purpose of work results in preparing of bacterial strains adapted to selected stress factors associated with production of PHAs from waste inexpensive substrates by methods of evolutionary engineering. Evolved strains will be modified by methods of genetic engineering to maximize production potential as well as control composition of copolymer of PHA considering properties of producing material. To gain strains with high robustness also extremophilic bacterial strains will be used.

I am going to participate in most experiments within the research. I will probably cooperate with all of my colleagues on evolutionary and genetic experiments and also on analysis of evolved strains as well as the analysis of the polymer which those strains produce.

Where I see myself in my career in 10 years

I would like to finish my PhD studies in 4 years. After I finish my studies, I would like to stay in my present research group at our faculty or work in research and development in some company in or near Brno dealing with biotechnology, pharmaceuticals etc.

What I like most about Brno
I appreciate the wide range of possibilities that Brno offers, both in terms of education and job opportunities, as well as the possibilities of cultural and sports activities in leisure, nature and other areas for its inhabitants.