Veronika Grézlová

Antibacterial Resorbable Polymer-phosphate Bone Filler for Bone Infection Treatment

Školitel: Assoc. prof. Lucy Vojtová, Ph.D.

Instituce: Brno University of Technology, CEITEC VUT

Obor: New antibacterial thixotropic resorbable polymer-phosphate bone fillers


O mém projektu

Each application of bone cement is disruption of body balance and infection may arise. This infection (osteomyelitis) is the main problem of modern reconstructive surgery. The defensive mechanism of the body has to be supported by the administration of antibiotics. This treatment is executed using the oral way and is less effective. The dose of the antibiotic should be high to provide ample concentration around the implantation. One possible solution is to add some antibacterial substances directly to bone cement.