Petra Lysáková

DNA Phenotyping: Predicting human appearance from historical skeletal material

Školitel: doc. RNDr. Eva Drozdová, Ph.D.

Instituce: Masaryk University, Faculty of Science

Obor: General and Molecular Genetics

 

O mém projektu

The phenotype is defined as an observable manifestation of a human genotype. The final phenotype color is determined by single nucleotide polymorphisms (SNPs) in the genes influencing the color shade. These SNPs are analyzed for phenotype determination. Typically and most frequently analyzed externally visible features (EVCs) include eye, hair, and skin colors. The aim of this project is to establish a protocol optimal for phenotype determination of aDNA to be able to predict the personal phenotype properly. The final goal of it is to describe the look of representatives of nobility in Czech lands, the Dietrichstein Dynasty, and the look of historical population of Slavs from the age of Great Moravia. The project includes testing of methods and protocols which are used or could be used for analyzing recent DNA and aDNA.