Mining genomic data for better stratification of patients with chronic lymphocytic leukemia
Školitel: Karla Plevová
Instituce: Masaryk University, Faculty of Science
O mém projektu
Chronic lymphocytic leukemia (CLL) is a molecularly heterogeneous disease with a highly variable prognosis. With the advent of massively parallel sequencing, there has been substantial progress in risk stratification and therapy for CLL, however, we are still unable to accurately stratify patients for particular treatments. In this project, we will explore patterns of genetic mutations and will aim to classify CLL cases into prognostic groups using somatic mutations data.