Irreversible electroporation on human cardiomyocytes as alternative ablative therapy for cardiac arrhythmias
Školitel: Martin Pešl
Instituce: Masaryk University, Faculty of Medicine
O mém projektu
The aim of the project is to limit the arrhythmic potential of native conductive tissue by inducing cellular apoptosis, in safer and targeted approach with respect to RF ablation. We ultimately propose to establish in vitro IRE protocols to control cellular fate in cardiac hPSC-CMs embryoid bodies (EBs), both isolated and in simulated tissue models.