Radovan Krejčíř

Pentamethinium salt derivatives as potential drugs for targeted cancer therapy – study of molecular and functional mechanisms

Školitel: RNDr. Bořivoj Vojtěšek, DrSc.

Instituce: Masaryk University, Faculty of Science

Obor: Molecular and cell biology

 

O mém projektu

Pentamethinium salt derivatives (PSDs) are novel compounds with potential to be used as drugs in targeted cancer therapy. Their anti-cancer activity was recently tested on cell lines and in vivo with promising results. Our ambition is to investigate biological properties of these compounds in detail. The project will be focused on mechanisms of cytotoxicity and cancer cell selectivity of PSDs. We hope that PSDs will be proven exploitable in cancer therapy.